Uncovering distinct progression patterns of tau deposition in progressive supranuclear palsy using [18F]Florzolotau PET imaging and subtype/stage inference algorithmResearch in context

Summary: Background: Progressive supranuclear palsy (PSP) is a primary 4-repeat tauopathy with diverse clinical phenotypes. Previous post-mortem studies examined tau deposition sequences in PSP, but in vivo scrutiny is lacking. Methods: We conducted [18F]Florzolotau tau positron emission tomography...

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Hlavní autoři:	Jimin Hong, Jiaying Lu, Fengtao Liu, Min Wang, Xinyi Li, Christoph Clement, Leonor Lopes, Matthias Brendel, Axel Rominger, Tzu-Chen Yen, Yihui Guan, Mei Tian, Jian Wang, Chuantao Zuo, Kuangyu Shi, Jianjun Wu, Yimin Sun, Ping Wu, Yilin Tang, Jue Zhao, Bin Wu, Bo Shen, Xinyue Zhou, Huiwei Zhang, Jingjie Ge, Minjia Chen, Zizhao Ju
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2023-11-01
Edice:	EBioMedicine
Témata:	Progressive supranuclear palsy [18F]Florzolotau tau positron emission tomography imaging Spatiotemporal trajectories Machine learning
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2352396423004012
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