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Dysregulated fibrinolysis and plasmin activation promote the pathogenesis of osteoarthritis

Joint injury is associated with risk for development of osteoarthritis (OA). Increasing evidence suggests that activation of fibrinolysis is involved in OA pathogenesis. However, the role of the fibrinolytic pathway is not well understood. Here, we showed that the fibrinolytic pathway, which include...

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Autori principali: Qian Wang, Guoqiang Shao, Xiaoyi Zhao, Heidi H. Wong, Kate Chin, Mackenzie Zhao, Audrey Bai, Michelle S. Bloom, Zelda Z. Love, Constance R. Chu, Zhen Cheng, William H. Robinson
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical investigation 2024-04-01
Serie:JCI Insight
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Accesso online:https://doi.org/10.1172/jci.insight.173603
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