Integrated virulence–resistance profiling of Helicobacter pylori reveals context-dependent pathogenic signatures in gastric cancer

BackgroundHelicobacter pylori contributes to gastric carcinogenesis through diverse virulence mechanisms, transcriptional plasticity, and rising antimicrobial resistance. However, how these features integrate into coordinated bacterial states within the tumor microenvironment remains unclear. This s...

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Hlavní autoři:	Oliver Mbuthia, Azhar Mehmood, Ishrat Mahjabeen, Mahmood A. Kayani, Jael Obiero, Takashi Matsumoto, Kefa Bosire, Marianne W. Mureithi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-05-01
Edice:	Frontiers in Cellular and Infection Microbiology
Témata:	antibiotic resistance (AMR) gastric cancer Helicobacter pylori k-means clustering molecular profiling transcriptional plasticity
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fcimb.2026.1812371/full
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