Prediction of potential NS3-based T cell epitopes of hepatitis C virus by in-silico and in-vitro approach

Abstract Due to the absence of an effective vaccine and suboptimal responses to direct-acting antivirals (DAA), Hepatitis C virus (HCV) genotype 3—prevalent in South Asia, the Middle East, and Central Asia—remains a significant public health challenge. This study aimed to identify conserved NS3-base...

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Hlavní autoři:	Supradip Dutta, Amlanjyoti Dhar, Meghamala Pande, Ankita Ghose, Moumita Majumdar, Sagnik Bakshi, Raina Das, Shreyasi Nath, Anwesha Ghosh, Provash Chandra Sadhukhan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-04-01
Edice:	Scientific Reports
Témata:	Epitope Docking of epitopes In-vitro validation of epitopes HCV T cell epitopes HCV NS3-based epitopes
On-line přístup:	https://doi.org/10.1038/s41598-026-49711-9
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