Design of a companion bioinformatic tool to detect the emergence and geographical distribution of SARS-CoV-2 Spike protein genetic variants

Abstract Background Tracking the genetic variability of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) is a crucial challenge. Mainly to identify target sequences in order to generate robust vaccines and neutralizing monoclonal antibodies, but also to track viral genetic temporal and g...

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Autors principals:	Alice Massacci, Eleonora Sperandio, Lorenzo D’Ambrosio, Mariano Maffei, Fabio Palombo, Luigi Aurisicchio, Gennaro Ciliberto, Matteo Pallocca
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2020-12-01
Col·lecció:	Journal of Translational Medicine
Matèries:	SARS-CoV-2 genome SARS-CoV-2 mutation COVID mutations SARS-CoV-2 vaccine Bioinformatic workflow Docker
Accés en línia:	https://doi.org/10.1186/s12967-020-02675-4
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