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Immunological and molecular signatures of carbamazepine-induced maculopapular exanthema

Cutaneous adverse drug reactions to carbamazepine range from mild maculopapular exanthema to life-threatening syndromes such as Stevens–Johnson syndrome/toxic epidermal necrolysis. While the immunological basis for HLA-B*15:02-restricted carbamazepine-induced SJS/TEN has received greater attention,...

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Sparad:
Huvudupphov: Kerry A. Mullan, Stephanie Davies, Kimberley Teoh, Hayley L. Tucker, Jeffrey W. Lai, Alison Anderson, Marian Todaro, Ching-Ching Ng, Kheng-Seang Lim, Johannes S. Kern, Patrick Kwan, Patricia T. Illing, Anthony W. Purcell, Nicole A. Mifsud
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2026-06-01
Serie:Frontiers in Immunology
Ämnen:
carbamazepine
drug hypersensitivity reaction
maculopapular exanthema
Stevens–Johnson syndrome
T-cell receptor
T-cells
Länkar:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1818888/full
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