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The pharmacokinetics (PK) / pharmacodynamics (PD) of pretomanid, delamanid and bedaquiline in the BALB/c mouse model of central nervous system tuberculosis

Abstract Background Central nervous system tuberculosis (CNS-TB) is one of the most destructive diseases with high morbidity and mortality worldwide. The present study aimed to assess the effect of three anti-tuberculosis drugs, pretomanid (PA-824), delamanid (DLM) and bedaquiline (BDQ), in CNS-TB t...

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Autors principals: Hui Zhu, Yangxue Ye, Lei Fu, Weiyan Zhang, Bin Wang, Xi Chen, Yu Lu
Format: Artigo
Idioma:Inglês
Publicat: BMC 2026-02-01
Col·lecció:BMC Infectious Diseases
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Accés en línia:https://doi.org/10.1186/s12879-026-12813-w
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