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Imaging mass cytometry dataset of small-cell lung cancer tumors and tumor microenvironments

Abstract Objectives Small cell lung cancer (SCLC) accounts for approximately 15% of lung tumors and is marked by aggressive growth and early metastatic spread. In this study, we used two SCLC mouse models with differing tumor mutation burdens (TMB). To investigate tumor composition, spatial architec...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: France Rose, Olta Ibruli, Luca Lichius, Martha Kiljan, Gokcen Gozum, Manoela Iannicelli Caiaffa, Jiali Cai, Li-na Niu, Jan M. Herter, Holger Grüll, Reinhard Büttner, Filippo Beleggia, Graziella Bosco, Julie George, Grit S. Herter-Sprie, Hans Christian Reinhardt, Katarzyna Bozek
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-09-01
Schriftenreihe:BMC Research Notes
Schlagworte:
SCLC
IMC
MIBI-TOF
Hyperion
Tumor microenvironment
Mouse models
Online-Zugang:https://doi.org/10.1186/s13104-025-07460-4
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