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Fibrillin-1 regulates periostin expression during maintenance of periodontal homeostasis

Background/purpose: Human periodontal ligament consists of elastic system fibers, mainly fibrillin-1 (FBN1). Periostin (POSTN) maintains periodontal homeostasis. A previous study showed that the expression of Postn in periodontal ligament cells was decreased in mice underexpressing Fbn1. However, th...

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Principais autores: Yoshikazu Manabe, Momotoshi Shiga, Kaori Kometani-Gunjigake, Kayoko Nakao-Kuroishi, Masahiro Mizuhara, Takashi Toyono, Yuji Seta, Tatsuo Kawamoto
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2022-10-01
Serier:Journal of Dental Sciences
Fag:
Human periodontal ligament fibroblasts
Fibrillin-1
Periostin
Periodontal homeostasis
TGF-β1
Online adgang:http://www.sciencedirect.com/science/article/pii/S1991790222000344
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