A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity

Summary: Lentiviral vectors (LVs) are highly efficient at inducing CD8+ T cell responses. However, LV-encoded antigens are processed inside the cytosol of antigen-presenting cells, which does not directly communicate with the endosomal major histocompatibility complex class II (MHC-II) presentation...

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Váldodahkkit:	Jodie Lopez, François Anna, Pierre Authié, Alexandre Pawlik, Min-Wen Ku, Catherine Blanc, Philippe Souque, Fanny Moncoq, Amandine Noirat, David Hardy, Wladimir Sougakoff, Roland Brosch, Françoise Guinet, Pierre Charneau, Laleh Majlessi
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Elsevier 2022-07-01
Ráidu:	Cell Reports
Fáttát:	CP: Immunology
Liŋkkat:	http://www.sciencedirect.com/science/article/pii/S2211124722009512
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