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Improvement of human embryonic stem cell-derived retinal pigment epithelium cell adhesion, maturation, and function through coating with truncated recombinant human vitronectin

AIM: To explore an xeno-free and defined coating substrate suitable for the culture of H9 human embryonic stem cell-derived retinal pigment epithelial (hES-RPE) cells in vitro, and compare the behaviors and functions of hES-RPE cells on two culture substrates, laminin521 (LN-521) and truncated recom...

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Principais autores: Xin-Yue Zhu, Yu-Hong Chen, Ting Zhang, Su-Jun Liu, Xin-Yue Bai, Xian-Yu Huang, Mei Jiang, Xiao-Dong Sun
Formato: Artigo
Idioma:Inglês
Publicado: Press of International Journal of Ophthalmology (IJO PRESS) 2021-08-01
Series:International Journal of Ophthalmology
Assuntos:
retinal pigment epithelial
stem cell
surface coating
laminin
vitronectin
cell adhesion
phagocytosis
Acceso en liña:http://ies.ijo.cn/en_publish/2021/8/20210804.pdf
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