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Cryptotaenia japonica extract attenuates glucocorticoid-induced muscle atrophy via regulation of the AKT/mTOR–FOXO/E3 ubiquitin ligase axis

Sarcopenia, characterized by progressive loss of skeletal muscle mass and function, is exacerbated by chronic glucocorticoid exposure, which activates catabolic signaling pathways and accelerates muscle protein degradation. Although Cryptotaenia japonica Hassk (Apiaceae) has been reported to possess...

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Autori principali: Da-In Choi, HuiJun Lee, Seokhoon Heo, Subin Cho, Pansoo Kim, Chul-Yung Choi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2026-07-01
Serie:Frontiers in Physiology
Soggetti:
Cryptotaenia japonica
FoxO signaling
glucocorticoids
mTOR pathway
muscle atrophy
sarcopenia
Accesso online:https://www.frontiersin.org/articles/10.3389/fphys.2026.1860064/full
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