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Critical pathomechanisms of NSAID-exacerbated respiratory disease (N-ERD) clarified by treatment with omalizumab, an anti-IgE antibody

Characteristic symptoms of NSAID-exacerbated respiratory disease (N-ERD) include asthma, chronic eosinophilic rhinosinusitis with nasal polyposis, cysteinyl LT (CysLT) overproduction and NSAIDs hypersensitivity. Some N-ERD patients present with episodic treatment-resistant extra-respiratory symptoms...

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Principais autores: Hiroaki Hayashi, Makoto Ishii, Yoshinori Hasegawa, Masami Taniguchi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-01-01
coleção:Allergology International
Assuntos:
Leukotriene E4
Mast cell
NSAID-exacerbated respiratory disease (N-ERD)
Omalizumab
Respiratory and extra-respiratory symptom
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1323893024001084
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