Clazosentan in aneurysmal subarachnoid hemorrhage: an updated systematic review and meta-analysis of efficacy and safety

Abstract Introduction Aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening neurological condition associated with high morbidity and mortality. Delayed cerebral ischemia (DCI), largely driven by cerebral vasospasm, remains a major determinant of poor outcomes. Clazosentan, a selective end...

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Principais autores:	Abdulelah Mohammed Alsakti, Zahra Hassan Al Ghazwi, Abdulrahman Khalid AlOtaibi, Mohammed Abdullah Alharbi, Layan Ali Aldeaiji, Abdulaziz Bijad Binshmilan, Naif Mohammed M. Alanazi, Rehaf Essa Alsharif, Fahad Mohammed Aldehaim, Basil Anas Alhindi, Norah Abdullah Alodhaib, Aalaa Saleh, Abdullah Altamimi
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2026-06-01
Series:	BMC Neurology
Assuntos:	Aneurysmal subarachnoid hemorrhage Clazosentan Cerebral vasospasm Delayed cerebral ischemia Meta-analysis
Acceso en liña:	https://doi.org/10.1186/s12883-026-05016-y
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