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Pharmacodynamic and pharmacokinetic properties of the combined preparation of levothyroxine plus sustained- release liothyronine; a randomized controlled clinical trial

Abstract Background Understanding pharmacokinetics (PK) and pharmacodynamics (PD) of the sustained-release liothyronine (SR-T3) is of paramount importance to design therapeutic regimens that are able to simulate normal thyroid hormone secretion while avoiding excursions in the T3 serum concentration...

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Principais autores: Ladan Mehran, Atieh Amouzegar, Seyed Mohsen Foroutan, Safdar Masoumi, Maryam Tohidi, Hengameh Abdi, Ali Aghaei, Amir Esmaeel Saghafinia, Fereidoun Azizi
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-08-01
Colecção:BMC Endocrine Disorders
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Acesso em linha:https://doi.org/10.1186/s12902-023-01434-y
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