A Selective Histamine H4 Receptor Antagonist, JNJ7777120, Is Protective in a Rat Model of Transient Cerebral Ischemia

Cerebral ischemia is a multifactorial pathology characterized by different events evolving in time. The acute injury, characterized by excitoxicity, is followed by a secondary brain injury that develops from hours to days after ischemia. Extracellular levels of histamine increase in the ischemic are...

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Egile Nagusiak:	Ilaria Dettori, Lisa Gaviano, Alessia Melani, Laura Lucarini, Mariaconcetta Durante, Emanuela Masini, Felicita Pedata
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2018-10-01
Saila:	Frontiers in Pharmacology
Gaiak:	H4 histamine receptor JNJ7777120 middle cerebral artery occlusion brain ischemia neuroinflammation rats
Sarrera elektronikoa:	https://www.frontiersin.org/article/10.3389/fphar.2018.01231/full
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