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Integrative analysis of a novel super-enhancer-associated lncRNA prognostic signature and identifying LINC00945 in aggravating glioma progression

Abstract Background Super-enhancers (SEs), driving high-level expression of genes with tumor-promoting functions, have been investigated recently. However, the roles of super-enhancer-associated lncRNAs (SE-lncRNAs) in tumors remain undetermined, especially in gliomas. We here established a SE-lncRN...

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Principais autores: Zhihao Yang, Yinfei Zheng, Haoyuan Wu, Han Xie, Jiajia Zhao, Zhigang Chen, Lianxin Li, Xiaoyu Yue, Bing Zhao, Erbao Bian
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-03-01
coleção:Human Genomics
Assuntos:
Super-enhancer
lncRNA
Prognostic signature
Immunotherapy
Glioma
Acesso em linha:https://doi.org/10.1186/s40246-023-00480-w
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