Effects of intestine-specific deletion of fibroblast growth factor 15 on alcoholic liver disease development in mice

Background and aims: Alcoholic liver disease (ALD) is an important and growing cause for the development of chronic liver diseases in the world. Bile acid (BA) levels are increased in patients with ALD and dysregulation of BA homeostasis worsens ALD. BA synthesis is critically regulated by fibroblas...

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Hlavní autoři:	Bo Kong, Mingxing Huang, Rulaiha E. Taylor, Daniel Rizzolo, Katherine D. Otersen, Grace L. Guo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	KeAi Communications Co., Ltd. 2022-06-01
Edice:	Liver Research
Témata:	Fibroblast growth factor 15 (FGF15) Farnesoid X receptor (FXR) Bile acid (BA) Alcoholic fatty liver disease Alcoholic steatohepatitis
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2542568422000198
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