Aspergillus fumigatus melanins: Interference with the host endocytosis pathway and impact on virulence

The opportunistic human pathogenic fungus Aspergillus fumigatus produces at least two types of melanin, namely pyomelanin and dihydroxynaphthalene (DHN) melanin. Pyomelanin is produced during tyrosine catabolism via accumulation of homogentisic acid. Although pyomelanin protects the fungus against r...

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Detalhes bibliográficos

Principais autores:	Thorsten eHeinekamp, Andreas eThywissen, Juliane eMacheleidt, Sophia eKeller, Vito eValiante, Axel A Brakhage
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2013-01-01
Colecção:	Frontiers in Microbiology
Assuntos:	Apoptosis Aspergillus fumigatus Endocytosis Phagocytes Virulence melanin
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00440/full
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