Extracellular Vesicles from Osteotropic Triple-Negative Breast Cancer Cells Transfer miRNAs to Bone Cells Reducing Collagen Expression and Bone Matrix Mineralisation

<b>Background/Objectives</b>: Bone metastases are a common complication of breast cancer. In our previous study, we reported that extracellular vesicles released by osteotropic human (MDA-MB-231) and murine (4T1) breast cancer cells disrupt bone homeostasis by enhancing osteoclast differentiation an...

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主要な著者:	Luca Giacchi, Argia Ucci, Elisa Pucci, Loreto Lancia, Fanny Pulcini, Simona Delle Monache, Nadia Rucci, Marco Ponzetti
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2026-03-01
シリーズ:	Pharmaceutics
主題:	breast cancer miRNAs bone metastases osteoclast osteoblast collagen
オンライン･アクセス:	https://www.mdpi.com/1999-4923/18/3/317
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