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Differential DNA methylation following chemotherapy for breast cancer is associated with lack of memory improvement at one year

The biological basis underlying cognitive dysfunction in women with early-stage breast cancer (BC) remains unclear, but could reflect gene expression changes that arise from the acquisition and long-term retention of soma-wide alterations in DNA methylation in response to chemotherapy. In this longi...

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Principais autores: Gee Su Yang, Xinlei Mi, Colleen K. Jackson-Cook, Angela R. Starkweather, Debra Lynch Kelly, Kellie J. Archer, Fei Zou, Debra E. Lyon
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2020-05-01
Serier:Epigenetics
Fag:
breast cancer
chemotherapy
epigenetics
dna methylation
chemo-brain
cognitive function
Online adgang:http://dx.doi.org/10.1080/15592294.2019.1699695
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