Crosstalk between protein kinases AKT and ERK1/2 in human lung tumor-derived cell models

There is no doubt that cell signaling manipulation is a key strategy for anticancer therapy. Furthermore, cell state determines drug response. Thus, establishing the relationship between cell state and therapeutic sensitivity is essential for the development of cancer therapies. In the era of person...

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Principais autores:	Aurimas Stulpinas, Matas Sereika, Aida Vitkeviciene, Ausra Imbrasaite, Natalija Krestnikova, Audrone V. Kalvelyte
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-01-01
coleção:	Frontiers in Oncology
Assuntos:	cancer cell cell signaling ERK (extracellular signal-regulated kinase) AKT kinase inhibitors targeted drugs
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fonc.2022.1045521/full
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