Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier[S]

Cardiac triacylglycerol (TG) catabolism critically depends on the TG hydrolytic activity of adipose triglyceride lipase (ATGL). Perilipin 5 (Plin5) is expressed in cardiac muscle (CM) and has been shown to interact with ATGL and its coactivator comparative gene identification-58 (CGI-58). Furthermor...

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Detalhes bibliográficos

Principais autores:	Nina M. Pollak, Martina Schweiger, Doris Jaeger, Dagmar Kolb, Manju Kumari, Renate Schreiber, Stephanie Kolleritsch, Philipp Markolin, Gernot F. Grabner, Christoph Heier, Kathrin A. Zierler, Thomas Rülicke, Robert Zimmermann, Achim Lass, Rudolf Zechner, Guenter Haemmerle
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2013-04-01
coleção:	Journal of Lipid Research
Assuntos:	adipose triglyceride lipase cardiac lipid energy metabolism
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022227520422126
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