Inhibitors of Lipoxygenase and Cyclooxygenase-2 Attenuate Trimethyltin-Induced Neurotoxicity through Regulating Oxidative Stress and Pro-Inflammatory Cytokines in Human Neuroblastoma SH-SY5Y Cells

Trimethyltin (TMT) is an environmental neurotoxin that mediates dopaminergic neuronal injury in the brain. In this study, we characterized the toxic mechanism and possible protective compounds against TMT-induced neurotoxicity in human dopaminergic neuroblastoma SH-SY5Y cells. Antioxidants such as m...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Woo-Ju Song, Jang-Hyuk Yun, Myeong-Seon Jeong, Kil-Nam Kim, Taekyun Shin, Hyoung-Chun Kim, Myung-Bok Wie
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	MDPI AG 2021-08-01
سلاسل:	Brain Sciences
الموضوعات:	apoptosis cyclooxygenase-2 esculetin lipoxygenase trimethyltin
الوصول للمادة أونلاين:	https://www.mdpi.com/2076-3425/11/9/1116
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!