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Loss of Snf5 Induces Formation of an Aberrant SWI/SNF Complex

Summary: The SWI/SNF chromatin remodeling complex is highly conserved from yeast to human, and aberrant SWI/SNF complexes contribute to human disease. The Snf5/SMARCB1/INI1 subunit of SWI/SNF is a tumor suppressor frequently lost in pediatric rhabdoid cancers. We examined the effects of Snf5 loss on...

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Autori principali: Payel Sen, Jie Luo, Arjan Hada, Solomon G. Hailu, Mekonnen Lemma Dechassa, Jim Persinger, Sandipan Brahma, Somnath Paul, Jeff Ranish, Blaine Bartholomew
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017-02-01
Serie:Cell Reports
Accesso online:http://www.sciencedirect.com/science/article/pii/S2211124717301821
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