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A Proof-of-Concept Study on the Therapeutic Potential of Au Nanoparticles Radiolabeled with the Alpha-Emitter Actinium-225

Actinium-225 (<sup>225</sup>Ac) is receiving increased attention for its application in targeted radionuclide therapy, due to the short range of its emitted alpha particles in conjunction with their high linear energy transfer, which lead to the eradication of tumor cells while sparing neighboring h...

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Autori principali: Evangelia-Alexandra Salvanou, Dimitris Stellas, Charalampos Tsoukalas, Barbara Mavroidi, Maria Paravatou-Petsotas, Nikolaos Kalogeropoulos, Stavros Xanthopoulos, Franck Denat, Gautier Laurent, Rana Bazzi, Stephane Roux, Penelope Bouziotis
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2020-02-01
Serie:Pharmaceutics
Soggetti:
actinium-225
alpha emitters
gold nanoparticles
radiolabeling
brachytherapy
cancer therapy
Accesso online:https://www.mdpi.com/1999-4923/12/2/188
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