txci-ATAC-seq: a massive-scale single-cell technique to profile chromatin accessibility
Abstract We develop a large-scale single-cell ATAC-seq method by combining Tn5-based pre-indexing with 10× Genomics barcoding, enabling the indexing of up to 200,000 nuclei across multiple samples in a single reaction. We profile 449,953 nuclei across diverse tissues, including the human cortex, mou...
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| Автори: | , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2024-03-01
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| Серія: | Genome Biology |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1186/s13059-023-03150-1 |
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