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Barcoding intracellular reverse transcription enables high-throughput phenotype-coupled T cell receptor analyses

Summary: Assays linking cellular phenotypes with T cell or B cell antigen receptor sequences are crucial for characterizing adaptive immune responses. Existing methodologies are limited by low sample throughput and high cost. Here, we present INtraCEllular Reverse Transcription with Sorting and sequ...

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Váldodahkkit: Sahana Jayaraman, Janelle M. Montagne, Thomas R. Nirschl, Emily Marcisak, Jeanette Johnson, Amanda Huff, Meng-Hsuan Hsiao, Julie Nauroth, Thatcher Heumann, Jelani C. Zarif, Elizabeth M. Jaffee, Nilo Azad, Elana J. Fertig, Neeha Zaidi, H. Benjamin Larman
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Elsevier 2023-10-01
Ráidu:Cell Reports: Methods
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Liŋkkat:http://www.sciencedirect.com/science/article/pii/S2667237523002527
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