Epidermal growth factor receptor inhibitors promote CNS axon growth through off-target effects on glia
Administration of epidermal growth factor receptor (EGFR) inhibitors (e.g. AG1478/PD168393) promotes central nervous system (CNS) axon regeneration in vivo by an unknown mechanism. Here, we show that EGFR activation is not required for AG1478-/PD168393-induced neurite outgrowth in cultures of dorsal...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2009-10-01
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| Col·lecció: | Neurobiology of Disease |
| Matèries: | |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S0969996109001764 |
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