Neural substrates of apathy in Parkinson’s disease: A systematic review of structural and functional neuroimaging studies

Background: Apathy is a frequent and disabling non-motor symptom in Parkinson’s disease (PD), characterized by diminished motivation, reduced goal-directed behavior, and emotional indifference. Growing evidence suggests that apathy in PD represents a distinct neuropsychiatric syndrome that may coexi...

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Detalhes bibliográficos

Principais autores:	Giulia Marafioti, Laura Culicetto, Carlo Blundo, Carla Susinna, Giovanni Restuccia, Giuseppe Di Lorenzo, Angelo Quartarone, Viviana Lo Buono
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-06-01
coleção:	Brain Research Bulletin
Assuntos:	Parkinson’s disease Apathy Neuroimaging Functional connectivity
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S036192302600208X
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