Functional Characterization of Small Alarmone Synthetase and Small Alarmone Hydrolase Proteins from Treponema denticola

ABSTRACT The stringent response enables bacteria to survive nutrient starvation, antibiotic challenge, and other threats to cellular survival. Two alarmone (magic spot) second messengers, guanosine pentaphosphate (pppGpp) and guanosine tetraphosphate (ppGpp), which are synthesized by RelA/SpoT homol...

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Principais autores:	Miao Wang, Nga-Yeung Tang, Shujie Xie, Rory M. Watt
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2023-08-01
coleção:	Microbiology Spectrum
Assuntos:	oral microbiome periodontal disease guanosine tetraphosphate spirochete ppApp enzyme kinetics
Acesso em linha:	https://journals.asm.org/doi/10.1128/spectrum.05100-22
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