GRP78 Nanobody‐Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy
Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies. Cell surface translocation of endoplasmic reticulum (ER) chaperones, such as glucose‐regulated protein 78 (GRP78), during malignancy, drug resistance, and ER stress induced by th...
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| Główni autorzy: | , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Wiley
2025-05-01
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| Seria: | Advanced Science |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1002/advs.202408086 |
| Etykiety: |
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