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Loss of the polarity protein Par3 promotes dendritic spine neoteny and enhances learning and memory

Summary: The Par3 polarity protein is critical for subcellular compartmentalization in different developmental processes. Variants of PARD3, encoding PAR3, are associated with intelligence and neurodevelopmental disorders. However, the role of Par3 in glutamatergic synapse formation and cognitive fu...

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Autori principali: Mikayla M. Voglewede, Elif Naz Ozsen, Noah Ivak, Matteo Bernabucci, Ruizhe Tang, Miao Sun, Zhiping P. Pang, Huaye Zhang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2024-07-01
Serie:iScience
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Accesso online:http://www.sciencedirect.com/science/article/pii/S2589004224015335
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