Bayesian trial of adalimumab versus secukinumab for children with juvenile idiopathic arthritis associated uveitis or chronic anterior uveitis

Abstract Background Juvenile idiopathic arthritis (JIA)-associated uveitis and chronic anterior uveitis in children may result in permanent sight loss. Currently, the only licensed and approved treatment for JIA-uveitis is adalimumab. However, even in patients where adalimumab may be initially effec...

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Detalhes bibliográficos

Principais autores:	Athimalaipet V Ramanan, Andrew D Dick, Thomas Jaki, Gianmarco Caruso, David S Robertson, Ashley P Jones, Ben Hardwick, Sian Drake, Balini Balasubramaniam, Coziana Ciurtin, Ivan Foeldvari, Elke O Kreps, Alice Leahy, Kristina May, Pierre Quartier, Matthieu P Robert, Gabriele Simonini, Catherine Guly, Michael W Beresford
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-05-01
coleção:	Pediatric Rheumatology Online Journal
Assuntos:	Juvenile idiopathic arthritis Uveitis Bayesian prior Clinical trial Biologics
Acesso em linha:	https://doi.org/10.1186/s12969-025-01107-1
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