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An essential and NSF independent role for α-SNAP in store-operated calcium entry

Store-operated calcium entry (SOCE) by calcium release activated calcium (CRAC) channels constitutes a primary route of calcium entry in most cells. Orai1 forms the pore subunit of CRAC channels and Stim1 is the endoplasmic reticulum (ER) resident Ca2+ sensor. Upon store-depletion, Stim1 translocate...

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Huvudupphov: Yong Miao, Cathrine Miner, Lei Zhang, Phyllis I Hanson, Adish Dani, Monika Vig
Materialtyp: Artigo
Språk:Inglês
Utgiven: eLife Sciences Publications Ltd 2013-07-01
Serie:eLife
Ämnen:
CRAC channel
SNAP
calcium
Orai
Stim
SOCE
Länkar:https://elifesciences.org/articles/00802
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