A TAp63alpha truncating variant associated with primary ovarian insufficiency lowers the cellular apoptotic rate
Abstract Background Primary ovarian insufficiency (POI) is a complex endocrine disorder with impairment of ovarian function before the age of 40 that can associate with mutations in TAp63alpha (TAp63α), a transcription factor essential for maintaining genome integrity in the female germline. Variant...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BMC
2025-12-01
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| Серии: | Journal of Ovarian Research |
| Предметы: | |
| Online-ссылка: | https://doi.org/10.1186/s13048-025-01881-2 |
| Метки: |
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