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RNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer

Abstract Triple-negative breast cancer (TNBC) is the most difficult breast cancer subtype to treat due to the lack of targeted therapies. Cancer stem cells (CSCs) are strongly enriched in TNBC lesions and are responsible for the rapid development of chemotherapy resistance and metastasis. Ubiquitin-...

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Principais autores: Evangelos Prokakis, Shaishavi Jansari, Angela Boshnakovska, Maria Wiese, Kathrin Kusch, Christof Kramm, Christian Dullin, Peter Rehling, Markus Glatzel, Klaus Pantel, Harriet Wikman, Steven A. Johnsen, Julia Gallwas, Florian Wegwitz
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2023-09-01
coleção:Cell Death and Disease
Acesso em linha:https://doi.org/10.1038/s41419-023-06157-5
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