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Methylation-to-Expression Feature Models of Breast Cancer Accurately Predict Overall Survival, Distant-Recurrence Free Survival, and Pathologic Complete Response in Multiple Cohorts

Abstract Prognostic biomarkers serve a variety of purposes in cancer treatment and research, such as prediction of cancer progression, and treatment eligibility. Despite growing interest in multi-omic data integration for defining prognostic biomarkers, validated methods have been slow to emerge. Gi...

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Autori principali: Jeffrey A. Thompson, Brock C. Christensen, Carmen J. Marsit
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2018-03-01
Serie:Scientific Reports
Accesso online:https://doi.org/10.1038/s41598-018-23494-0
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