Loss of Drosophila Coq8 results in impaired survival, locomotor deficits and photoreceptor degeneration

Abstract Coenzyme Q8A encodes the homologue of yeast coq8, an ATPase that is required for the biosynthesis of Coenzyme Q10, an essential component of the electron transport chain. Mutations in COQ8A in humans result in CoQ10 deficiency, the clinical features of which include early-onset cerebellar a...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Angelia J. Hura, Hannah R. Hawley, Wei Jun Tan, Rebecca J. Penny, Jessie C. Jacobsen, Helen L. Fitzsimons
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2022-02-01
Цуврал:	Molecular Brain
Нөхцлүүд:	coq8 COQ8A Coenzyme Q10 Brain Neuron Drosophila
Онлайн хандалт:	https://doi.org/10.1186/s13041-022-00900-3
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!