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Targeting the Sarcomere: Myosin Inhibitors as the Revolutionary Game Changer in Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HCM) represents the most common inherited cardiac disease and a leading cause of heart failure, arrhythmias, and sudden cardiac death in young individuals. For decades, management of HCM has relied on symptom control with β-blockers, calcium channel blockers, disopyramid...

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Principais autores: Farbod Sedaghat-Hamedani, Elham Kayvanpour, Benjamin Meder
Format: Artigo
Sprog:Inglês
Udgivet: IMR Press 2026-01-01
Serier:Reviews in Cardiovascular Medicine
Fag:
hypertrophic cardiomyopathy
myosin inhibitors
myosin heavy chains
mavacamten
aficamten
precision medicine
Online adgang:https://www.imrpress.com/journal/RCM/27/1/10.31083/RCM47341
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