Working correlates of protection predict SchuS4-derived-vaccine candidates with improved efficacy against an intracellular bacterium, Francisella tularensis

Abstract Francisella tularensis, the causative agent of tularemia, is classified as Tier 1 Select Agent with bioterrorism potential. The efficacy of the only available vaccine, LVS, is uncertain and it is not licensed in the U.S. Previously, by using an approach generally applicable to intracellular...

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Auteurs principaux:	Roberto De Pascalis, Blake Frey, Helen M. Rice, Varunika Bhargava, Terry H. Wu, Ross L. Peterson, J. Wayne Conlan, Anders Sjöstedt, Karen L. Elkins
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2022-08-01
Collection:	npj Vaccines
Accès en ligne:	https://doi.org/10.1038/s41541-022-00506-9
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