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Adjuvant therapy for renal cell carcinoma: lessons from past failures and new opportunities in the era of immune checkpoint inhibition

Renal cell carcinoma (RCC) has historically posed a significant therapeutic challenge in the adjuvant setting. Although surgical resection remains the cornerstone of curative-intent treatment for localized disease, a substantial proportion of patients with high-risk pathological features will experi...

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Principais autores: Zengguang Liu, Xiaofeng Cong, Ziyi Liu, Jiaxin Yin, Chen Chen, Ziling Liu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-04-01
Serier:Frontiers in Immunology
Fag:
adjuvant therapy
biomarker-driven stratification
immune checkpoint inhibitors
pembrolizumab
precision oncology
renal cell carcinoma
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1816253/full
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