Chaperone-mediated autophagy modulates Snail protein stability: implications for breast cancer metastasis

Abstract Breast cancer remains a significant health concern, with triple-negative breast cancer (TNBC) being an aggressive subtype with poor prognosis. Epithelial-mesenchymal transition (EMT) is important in early-stage tumor to invasive malignancy progression. Snail, a central EMT component, is tig...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Ki-Jun Ryu, Ki Won Lee, Seung-Ho Park, Taeyoung Kim, Keun-Seok Hong, Hyemin Kim, Minju Kim, Dong Woo Ok, Gu Neut Bom Kwon, Young-Jun Park, Hyuk-Kwon Kwon, Cheol Hwangbo, Kwang Dong Kim, J. Eugene Lee, Jiyun Yoo
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-10-01
Schriftenreihe:	Molecular Cancer
Schlagworte:	Chaperone-mediated autophagy Snail EMT Metastasis Breast cancer
Online-Zugang:	https://doi.org/10.1186/s12943-024-02138-0
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