Rapid and Efficient Access to Novel Bio-Inspired 3-Dimensional Tricyclic SpiroLactams as Privileged Structures via Meyers’ Lactamization

The concept of privileged structure has been used as a fruitful approach for the discovery of novel biologically active molecules. A privileged structure is defined as a semi-rigid scaffold able to display substituents in multiple spatial directions and capable of providing potent and selective liga...

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Principais autores:	Salia Tangara, Léo Faïon, Catherine Piveteau, Frédéric Capet, Romain Godelier, Marion Michel, Marion Flipo, Benoit Deprez, Nicolas Willand, Baptiste Villemagne
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-03-01
coleção:	Pharmaceuticals
Assuntos:	focused chemical library natural-like products tricyclic spirolactams Fsp<sup>3</sup>-rich compounds privileged scaffolds
Acesso em linha:	https://www.mdpi.com/1424-8247/16/3/413
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