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Functional link between sarcoidosis-associated gene variants and quantitative levels of bronchoalveolar lavage fluid cell types

BackgroundSarcoidosis is an inflammatory disease that affects multiple organs. Cell analysis from bronchoalveolar lavage fluid (BALF) is a valuable tool in the diagnostic workup and differential diagnosis of sarcoidosis. Besides the expansion of lymphocyte expression-specific receptor segments (Vα2....

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Principais autores: Muntasir Abo Al Hayja, Susanna Kullberg, Anders Eklund, Leonid Padyukov, Johan Grunewald, Natalia V. Rivera
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-02-01
Serier:Frontiers in Medicine
Fag:
sarcoidosis
single nucleotide polymorphisms
immunogenetics
eQTLs
gene regulation
HLA
Online adgang:https://www.frontiersin.org/articles/10.3389/fmed.2023.1061654/full
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