Role of membrane-embedded drug efflux ABC transporters in the cancer chemotherapy

One of the major problems being faced by researchers and clinicians in leukemic treatment is the development of multidrug resistance (MDR) which restrict the action of several tyrosine kinase inhibitors (TKIs). MDR is a major obstacle to the success of cancer chemotherapy. The mechanism of MDR invol...

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Detalhes bibliográficos

Principais autores:	Sonu Kumar Gupta, Priyanka Singh, Villayat Ali, Malkhey Verma
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2020-07-01
coleção:	Oncology Reviews
Assuntos:	ABC transporter breast cancer resistance protein (BCRP) chronic myeloid leukemia (CML) multidrug resistance (MDR) P-glycoprotein.
Acesso em linha:	https://www.oncologyreviews.org/site/article/view/448
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