The mitochondrial RNA polymerase POLRMT promotes skin squamous cell carcinoma cell growth
Abstract RNA polymerase mitochondrial (POLRMT) expression and the potential biological functions in skin squamous cell carcinoma (SCC) were explored. We showed that POLRMT is significantly elevated in skin SCC. Genetic depletion of POLRMT, using shRNA-induced knockdown or CRISPR/Cas9-mediated knocko...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2022-08-01
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| coleção: | Cell Death Discovery |
| Acesso em linha: | https://doi.org/10.1038/s41420-022-01148-5 |
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