Sub-regional hippocampal injury is associated with fornix degeneration in Alzheimer's disease

We examined in vivo evidence of axonal degeneration in association with neuronal pathology in Alzheimer’s disease (AD) through analysis of fornix microstructural integrity and measures of hippocampal subfield atrophy. Based on known anatomical topography, we hypothesized that the local thickness of...

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Detalhes bibliográficos

Principais autores:	Dong Young Lee, Evan eFletcher, Owen Thomas Carmichael, Baljeet eSingh, Dan eMungas, Bruce eReed, Oliver eMartinez, Michael H Buonocore, Maria ePersianinova, Charles eDeCarli
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2012-04-01
coleção:	Frontiers in Aging Neuroscience
Assuntos:	Hippocampus Mild Cognitive Impairment Alzheimer's disease Fornix fractional anisotropy
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fnagi.2012.00001/full
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