Angiotensin II Type I Receptor (AT1R): The Gate towards COVID-19-Associated Diseases

The binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein to its cellular receptor, the angiotensin-converting enzyme 2 (ACE2), causes its downregulation, which subsequently leads to the dysregulation of the renin–angiotensin system (RAS) in favor of the ACE–...

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Bibliografski detalji

Glavni autori:	George El-Arif, Shaymaa Khazaal, Antonella Farhat, Julien Harb, Cédric Annweiler, Yingliang Wu, Zhijian Cao, Hervé Kovacic, Ziad Abi Khattar, Ziad Fajloun, Jean-Marc Sabatier
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-03-01
Serija:	Molecules
Teme:	SARS-CoV-2 COVID-19 Ang II–AT1R axis ACE2 AT1R downstream signaling pathways multiple system damages
Online pristup:	https://www.mdpi.com/1420-3049/27/7/2048
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