Progression patterns, resistant mechanisms and subsequent therapy for ALK-positive NSCLC in the era of second-generation ALK-TKIs

Abstract Background In the era of second-generation ALK tyrosine kinase inhibitors (ALK-TKIs), there was a paucity of data regarding the progression patterns, resistant mechanisms, and subsequent therapeutic approaches for ALK-positive (ALK+) non-small cell lung cancer (NSCLC). Methods Patients with...

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Bibliografische Detailangaben

Hauptverfasser:	Lige Wu, Zihua Zou, Yan Li, Xuezhi Hao, Jianming Ying, Junling Li, Puyuan Xing
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-06-01
Schriftenreihe:	Journal of Translational Medicine
Schlagworte:	ALK NSCLC Real-world study Resistance
Online-Zugang:	https://doi.org/10.1186/s12967-024-05388-0
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